Article
Soluble CD14: genomewide association analysis and relationship to cardiovascular risk and mortality in older adults.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jan 2013
Reiner Alex P, Lange Ethan M, Jenny Nancy S, Chaves Paulo H M, Ellis Jaclyn, Li Jin, Walston Jeremy, Lange Leslie A, Cushman Mary, Tracy Russell P
Abstract excerpt
OBJECTIVE: CD14 is a glycosylphosphotidylinositol-anchored membrane glycoprotein expressed on neutrophils and monocytes/macrophages that also circulates as a soluble form (sCD14). Despite the well-recognized role of CD14 in inflammation, relatively little is known about the genetic determinants of sCD14 or the relationship of sCD14 to vascular- and aging-related phenotypes. METHODS AND RESULTS: We measured...
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