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Article

Functions, interactions and prognostic role of POLE: a bioinformatics analysis.

Journal of gynecologic oncology - 1 May 2025

Carvajal-Veloza Jonathan, Galindo-Morales Fredy, Gutierrez-Castañeda Luz Dary

Abstract excerpt

OBJECTIVE: To describe POLE characteristics and reported mutations in endometrial cancer (EC) and analyze the impact of these mutations on the structure and function of the protein, as well as their relationship with the survival and prognosis of the disease. METHODS: We retrieved reported mutations for POLE in EC from Catalogue of Somatic Mutations in Cancer database. We analyzed the most frequent mutations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39575998
DOI: 10.3802/jgo.2025.36.e45
PMCID: PMC12099036

Genes

POLE
CD4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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