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Exploring the genetic associations and causal relationships between antibody responses, immune cells, and various types of breast cancer.

Scientific reports - 19 Nov 2024

Yang Yang, Chen Jiayi, Gong Fuhong, Miao Jingge, Lin Mengping, Liu Ruimin, Wang Chenxi, Ge Fei, Chen Wenlin

Abstract excerpt

BACKGROUND: There may be potential associations between various pathogens, antibody immune responses, and breast cancer (BC), but the specific mechanisms and causal relationships remain unclear. METHODS: First, multiple Mendelian randomization (MR) methods were used for univariable MR analysis to explore potential causal relationships between 34 antibody immune responses (related to 12 pathogens), 46 antibody...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39562684
DOI: 10.1038/s41598-024-79521-w
PMCID: PMC11577091

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