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Article

Causal association between blood immune cells and chronic hepatitis B: Univariable and multivariable Mendelian randomization.

Medicine - 9 Jan 2026

Dong Jianhui, Peng Ziting, Qin Chaofan, Shi Tongdong

Abstract excerpt

Current evidence underscores the pivotal role of the immune system in the pathogenesis of chronic hepatitis B (CHB). Nevertheless, the precise causal nexus between immune cells and CHB remains enigmatic, with numerous unresolved queries. Leveraging data from the latest summary-level genome-wide association studies, we examined immune cell genetics in 3757 individuals from Sardinia. CHB data predominantly...

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Genetic Predisposition to Disease
Genome-Wide Association Study
Hepatitis B, Chronic
Mendelian Randomization Analysis
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 41517674
DOI: 10.1097/MD.0000000000047011
PMCID: PMC12795022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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