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Article

Causal Links Between Antibody-Mediated Immune Responses and Pancreatic Cancer Risk.

Endocrine, metabolic & immune disorders drug targets - 1 Jan 2026

Zou Xinyun, Feng Yicheng, Liu Pei, Zhang Ling, Shen Jinlan

Abstract excerpt

INTRODUCTION: Pancreatic cancer (PC) presents unique challenges to traditional immunotherapy due to its immunosuppressive microenvironment and low mutation burden. Research into antibody-mediated immune responses, which has been extensively applied in various cancer types, is also applicable to the study of pancreatic cancer. METHODS: Using public Genome-wide association study (GWAS) data and genetic instruments,...

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Topics

Humans
Pancreatic Neoplasms
Genome-Wide Association Study
Risk Factors
Mendelian Randomization Analysis
Genetic Predisposition to Disease

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Identifiers

PMID: 41185498
DOI: 10.2174/0118715303396420251007140802
PMCID: PMC13662728

Genes

PC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

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