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Article

Causal relationships between immune cell phenotypes and lung adenocarcinoma: A bidirectional two-sample Mendelian randomization study.

Thoracic cancer - 1 Jul 2024

Li Bowen, Huang Zhicheng, Wang Yadong, Guo Chao, Liang Naixin, Yang Huaxia, Li Shanqing

Abstract excerpt

BACKGROUND: Lung adenocarcinoma (LUAD) is the most common type of lung cancer and closely associated with the immune system. Emerging evidence suggests that blood immune cell phenotypes in patients with LUAD may undergo alterations. Nevertheless, the limited amount of relevant research makes it difficult to understand the causal links between LUAD and changes in the immune cells. This study aimed to reveal the...

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Adenocarcinoma of Lung
Lung Neoplasms
Mendelian Randomization Analysis
Phenotype

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39034427
DOI: 10.1111/1759-7714.15394
PMCID: PMC11260555

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