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Article

Immune Cell Profiles and Novel Insights Into Cancer Risk: A Focus on Oral and Pharyngeal Cancer.

Human mutation - 1 Jan 2026

Deng Xin, Huang Shaohong

Abstract excerpt

Background and Objective: Oral and pharyngeal cancers affect 850,000 new cases annually with 440,000 deaths worldwide. This study explores the causal relationship between immune cell profiles and oral-pharyngeal cancer risk through Mendelian randomization analysis integrated with experimental validation. Methods: A two-sample Mendelian randomization study was conducted using the MRC IEU OpenGWAS platform,...

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CD4 gene
Genetic Predisposition to Disease
Genome-Wide Association Study
Mendelian Randomization Analysis
Mouth Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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PMID: 42428247
DOI: 10.1155/humu/6585175
PMCID: PMC13347225

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CD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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