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Article

Causal insights into immune cell profiles, plasma metabolites, and bladder cancer: A Mendelian randomization approach.

Medicine - 21 Nov 2025

Yang Juan, Xu Zhangxiao, Tao Bo, Zhao Yuan, Ma Yiran, Niu Yuanjian, He Yunpeng, Wu Jian, Wang Lijun, Zhong Zitao

Abstract excerpt

This study aimed to investigate the causal associations between immune cells, plasma metabolites, and bladder cancer (BC) using Mendelian randomization (MR). Utilizing summary data from genome-wide association studies, the study examined the causal effects among 731 immune cell phenotypes, 1400 plasma metabolites, and BC. Bidirectional MR analysis was conducted to assess the links between immune cells and BC, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41305704
DOI: 10.1097/MD.0000000000046062
PMCID: PMC12643734

Genes

CD19
CD24
CD4
C7
CD27
CD38

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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