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Article

Association of immune cells with the risk of basal cell carcinoma: A bidirectional Mendelian randomized study.

Medicine - 26 Sept 2025

Wang Suyao, Li Yuying, Huang Shaolei

Abstract excerpt

Basal cell carcinoma (BCC) is globally recognized as the most prevalent malignant skin tumor. Despite ample evidence suggesting that immune cells play a significant role in its development, the causal relationship between the 2 remains unclear. This study employed the Mendelian randomization (MR) analysis approach, utilizing publicly available genome-wide association studies data on 731 immune cell phenotypes and...

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Topics

Humans
Basal Cell Carcinoma
Mendelian Randomization Analysis
Skin Neoplasms
Genome-Wide Association Study
Risk Factors

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Identifiers

PMID: 41029081
DOI: 10.1097/MD.0000000000044656
PMCID: PMC13593114

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