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Article

Genetically predicted Caspase 8 levels mediates the causal association between CD4+ T cell and breast cancer.

Frontiers in immunology - 1 Jan 2024

Chen Yanbin, Zheng Zequn, Wang Jinhong, Huang Xifeng, Xie Lei

Abstract excerpt

Background: Breast cancer (BC) remains a significant contributor to female mortality globally, with inflammation and the immune system implicated in its pathogenesis. To elucidate potential causal relationships, we evaluated the relationship among 731 immune cell phenotypes and BC be at risk by using Mendelian randomization (MR), while also exploring inflammatory proteins as mediators in this association....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39391306
DOI: 10.3389/fimmu.2024.1410994
PMCID: PMC11464308

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CD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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