Article
Phenotype and genotype alteration during adaptive evolution of Enterococcus faecalis to antimicrobials.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Aug 2018
Sun Yao, Lu Hong, Zhang Xiaoxiao, Wu Qing, Bi Wenzi, Liu Haiyang, Cao Jianming, Zhou Tieli
Abstract excerpt
The current worldwide emergence of resistance to antibiotics in bacteria constitutes an important growing public health threat. The mechanisms of the emergence and dissemination of resistance remain to be elucidated. Adaptation laboratory evolution provide an approach to investigate the acquisition of de novo mutations that confers drug resistance. In our study, 3 Enterococcus faecalis clinical isolates and E....
Topics
- Adaptation, Physiological
- Anti-Bacterial Agents
- Biological Evolution
- Drug Resistance, Multiple, Bacterial
- Enterococcus faecalis
- Genotype
- Microbial Sensitivity Tests