Article

Antibiotics of the future are prone to resistance in Gram-negative pathogens

2023-07-23

Abstract excerpt

Despite the ongoing development of new antibiotics, the future evolution of bacterial resistance may render them ineffective. We demonstrate that antibiotic candidates currently under development are as prone to resistance evolution in Gram-negative pathogens as clinically employed antibiotics. Resistance generally stems from both genomic mutations and the transfer of antibiotic resistance genes from microbiomes a...

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Literature Corpus work: f606b30a-27f6-5b0f-957b-2bf3d5724bb4
DOI: 10.1101/2023.07.23.550022

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