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Article

CCN3/NOV as a potential therapeutic target for diverticular disease: A proteome-wide Mendelian randomization study.

Medicine - 8 Nov 2024

Yoshikawa Masahiro, Asaba Kensuke

Abstract excerpt

Genome-wide association studies (GWAS) identified over 100 susceptibility loci and candidate causal genes for diverticular disease (DD) at the transcriptional level. However, effective therapeutics or preventions based on underlying disease mechanisms remain to be elucidated. In this study, we explored potential causal genes for DD at the protein level. We used 2 GWAS summary statistics of DD; 1 was obtained from...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 39533633
DOI: 10.1097/MD.0000000000040467
PMCID: PMC11557123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

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