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Article

Proteome-Wide Mendelian Randomization Identifies Causal Links Between Blood Proteins and Acute Pancreatitis.

Gastroenterology - 1 May 2023

Bourgault Jérôme, Abner Erik, Manikpurage Hasanga D, Pujol-Gualdo Natàlia, Laisk Triin, Gobeil Émilie, Gagnon Eloi, Girard Arnaud, Mitchell Patricia L, Thériault Sébastien, Esko Tõnu, Mathieu Patrick, Arsenault Benoit J

Abstract excerpt

BACKGROUND & AIMS: Acute pancreatitis (AP) is a complex disease and the leading cause of gastrointestinal disease-related hospital admissions. Few therapeutic options exist for AP prevention. Blood proteins with causal evidence may represent promising drug targets, but few have been causally linked with AP. Our objective was to identify blood proteins linked with AP by combining genome-wide association...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36736436
DOI: 10.1053/j.gastro.2023.01.028

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