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Article

Genetic determinants of cerebrospinal fluid metabolites and risk of Guillain-Barré syndrome: A bidirectional two-sample Mendelian randomization study.

Medicine - 8 Nov 2024

Qi Xiangjia, Gao Liqian, Qi Lifeng

Abstract excerpt

This study aims to investigate the potential causal relationship between cerebrospinal fluid (CSF) metabolites and Guillain-Barré syndrome (GBS) using a bidirectional two-sample Mendelian randomization (MR) approach. Publicly available summary data from genome-wide association studies (GWAS) were utilized for comprehensive analysis. The CSF metabolite GWAS summary data were extracted from a GWAS conducted by...

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PMID: 39533579
DOI: 10.1097/MD.0000000000040352
PMCID: PMC11557065

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