Article
Cerebrospinal fluid metabolites and multiple sclerosis: A two-sample Mendelian randomization study.
Medicine - 2 Jan 2026
Zhang Dejin, Feng Jiaojiao, Feng Jing, Chen Gang
Abstract excerpt
Epidemiological evidence suggests that cerebrospinal fluid (CSF) metabolites are associated with multiple sclerosis (MS). However, the causality remains unclear as a consequence of confounding or reverse causation. As a result, we evaluated the causal relationship between CSF metabolites and MS. A 2-sample Mendelian randomization analysis was performed for 338 CSF metabolites and MS, with causal relationship...
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