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Article

Measuring the impact of therapy-induced senescence on NK cell phenotypes in cancer.

Methods in cell biology - 1 Jan 2024

Chowdhury Shreya R, Murphy Katherine C, Parikh Chaitanya N, DeMarco Kelly D, Zhou Lin, Ruscetti Marcus

Abstract excerpt

Cellular senescence is a damage-induced condition characterized by enduring cell cycle arrest and a heightened secretory profile known as the senescence-associated secretory phenotype (SASP). The SASP consists not only of release of inflammatory cytokines and chemokines that attract and activate a diverse repertoire of innate and adaptive immune cells, but also the upregulation of immunomodulatory cell surface...

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Identifiers

PMID: 39515879
DOI: 10.1016/bs.mcb.2024.07.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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