Article
Senescence and the tumor-immune landscape: Implications for cancer immunotherapy.
Seminars in cancer biology - 1 Nov 2022
Chibaya Loretah, Snyder Jarin, Ruscetti Marcus
Abstract excerpt
Cancer therapies, including conventional chemotherapy, radiation, and molecularly targeted agents, can lead to tumor eradication through a variety of mechanisms. In addition to their effects on tumor cell growth and survival, these regimens can also influence the surrounding tumor-immune microenvironment in ways that ultimately impact therapy responses. A unique biological outcome of cancer therapy is induction...
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