Article
Genetically predicted inflammatory cytokine levels and risk of retinitis pigmentosa.
Ophthalmic genetics - 1 Feb 2025
Ren He, Zhang Danlei, Lu Mingzhi, Chen Zhen, Xing Yiqiao
Abstract excerpt
PURPOSE: This study aims to estimate the potential causal relationship between genetically predicted levels of inflammatory cytokine and retinitis pigmentosa (RP) by performing Mendelian randomization (MR). METHODS: Single nucleotide polymorphisms (SNPs) were identified as instrumental variables (IVs) from publicly available genome-wide association study datasets. Inverse-variance weighted (IVW), MR-Egger,...
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