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Article

Inflammation and keratoconus: A comprehensive bidirectional Mendelian randomization analysis.

Medicine - 26 Jul 2024

Zhang Xueyan, Cui Fenghua, Wang Qiaoling, Zhang Chenming

Abstract excerpt

An increasing body of evidence supports the involvement of inflammation and immune responses in the occurrence and development of keratoconus (KC). However, the causal relationship between inflammatory factors and KC remains unclear. We employed a 2-way Mendelian randomization (MR) approach to investigate the interaction between KC and inflammatory factors. Instrumental variables for 41 circulating inflammatory...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39058875
DOI: 10.1097/MD.0000000000039067
PMCID: PMC11272297

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