Article
Causal role of immune cells in uveitis: Mendelian randomization study.
Frontiers in immunology - 1 Jan 2024
Wu Jiahui, Fang Caocao, Zhou Yongwei, Wang Menghua, Li Qiuming, Dong Shuqian
Abstract excerpt
Background: Uveitis, characterized by inflammation of the iris, ciliary body, and choroid, presents a significant global clinical challenge, contributing substantially to visual impairment. Risk factors include autoimmune diseases and immune cell dysfunctions, yet many remain unidentified. Immune cells, notably T cells, B cells, and monocytes, play pivotal roles in uveitis pathogenesis. While biologic agents show...
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