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Article

The causal relationship between immune cells and diabetic retinopathy: a Mendelian randomization study.

Frontiers in immunology - 1 Jan 2024

Ye Yunyan, Dai Lei, Gu Hong, Yang Lan, Xu Zhangxing, Li Zhiguo

Abstract excerpt

Purpose: This article explored the causal relationship between immune cells and diabetic retinopathy (DR) using single nucleotide polymorphisms (SNPs) as an instrumental variable and Mendelian randomization (MR). Methods: Statistical data were collected from a publicly available genome-wide association study (GWAS), and SNPs that were significantly associated with immune cells were used as instrumental variables...

Topics

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Diabetic Retinopathy
CD14 gene
CD4 gene
Genetic Predisposition to Disease
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mendelian Randomization Analysis

Polymorphism, Single Nucleotide

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Identifiers

PMID: 39290701
DOI: 10.3389/fimmu.2024.1381002
PMCID: PMC11406504

Genes

CD14
CD33
CD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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