Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Causal Relationship between Immune-Mediated Inflammatory Diseases and Aortic Aneurysm: A Bidirectional Two-Sample Mendelian Randomization Study.

Journal of immunology research - 1 Jan 2024

Sun Sijia, Li Jie, Sun Mengxian, He Jie, Tan Songtao, Wang Ge, Zheng Yuan, Fan Xiaoping

Abstract excerpt

Methods: We sourced genetic association data from public genome-wide association study databases for populations of European ancestry. Adhering to MR principles, we identified valid instrumental variables from genetic variants. A range of statistical methods were applied for MR analysis, with the inverse variance weighted (IVW) method emerging as the most reliable estimator of causality in this context. Results:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aortic Aneurysm
Share to Arthritis, Rheumatoid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Crohn Disease

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Inflammation

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 39421304
DOI: 10.1155/2024/2474118
PMCID: PMC11483648

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Causal Relationship between Immune-Mediated Inflammatory Diseases and Aortic Aneurysm: A Bidirectional Two-Sample Mendelian Randomization Study.PMID 39421304Read ↗

The causal relationship between immune-mediated inflammatory diseases and aortic aneurysm: A bidirectional two-sample Mendelian randomization studySemantic proximity Read ↗

Genetic association between immune-mediated inflammatory diseases and peripheral artery disease: A Mendelian Randomization StudySemantic proximity Read ↗

Genetic association between immune-mediated inflammatory diseases and peripheral artery disease: a Mendelian randomization studySemantic proximity Read ↗

sIL-6R impact on aortic aneurysm: Genetic evidence from FinnGen and GWAS.Semantic proximity Read ↗

Assessing the causal relationship between circulating immune cells and abdominal aortic aneurysm by bi-directional Mendelian randomization analysis.Semantic proximity Read ↗

Causal association between circulating inflammatory proteins and peripheral artery disease: a bidirectional two-sample Mendelian randomization study.Semantic proximity Read ↗

Exploring the Causal Link Between Autoimmune Diseases and Pulmonary Arterial Hypertension: A Bidirectional Mendelian Randomization Study.Semantic proximity Read ↗

Causal Effect of Multicohort Circulating Proteome on the Risk of Aortic Aneurysm: A Mendelian Randomization Study.Semantic proximity Read ↗

Immune-mediated inflammatory diseases and the risk of valvular heart disease: a Mendelian randomization study.Semantic proximity Read ↗

Genetic causal association between lipidomic profiles, inflammatory proteomics, and aortic stenosis: a Mendelian randomization investigation.Semantic proximity Read ↗

Circulating inflammatory cytokines and risk of aortic stenosis: A Mendelian randomization analysis.Semantic proximity Read ↗

Causal Effect of Multi-cohort Circulating Proteome on the Risk of Aortic Aneurysm: A Mendelian Randomization StudySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.