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Article

Exploring the Causal Link Between Autoimmune Diseases and Pulmonary Arterial Hypertension: A Bidirectional Mendelian Randomization Study.

Global heart - 1 Jan 2025

Ma Chao, Gong Cheng, Wang Bin, Li Yangmeina, Qian Yongxiang, Zhang Xiaoying, Di Dongmei, Wang Min

Abstract excerpt

Background: Pulmonary arterial hypertension (PAH) is a severe vascular disorder with a multifactorial etiology, including potential genetic predispositions. Understanding the causal relationship between autoimmune diseases and the risk of developing PAH can inform clinical strategies for prevention and treatment. Methods: We conducted a two-sample Mendelian Randomization (MR) analysis to evaluate the causal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40620598
DOI: 10.5334/gh.1445
PMCID: PMC12227091

Genes

PAH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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