Article
Immune-mediated inflammatory diseases and the risk of valvular heart disease: a Mendelian randomization study.
Clinical rheumatology - 1 Jan 2024
Cai Dihui, Zheng Zequn, Hu Jiale, Fu Yin, Song Yongfei, Lian Jiangfang
Abstract excerpt
BACKGROUND: Observational studies have suggested that immune-mediated inflammatory diseases (IMIDs) are associated with a higher risk of valvular heart disease (VHD). But the potential causal association is not clear. Therefore, we used Mendelian randomization (MR) analysis to assess the causal association of IMIDs with VHD risk. METHODS: A two-sample MR analysis was performed to confirm the causal association of...
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