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Circulating inflammatory cytokines and risk of aortic stenosis: A Mendelian randomization analysis.

Cytokine - 1 May 2025

Qiu Xiaohan, Wu Jijun, Chen Zehao, Zhang Yu, Cao Luying, Wang Ning, Teng Junlin, Su Cong, Cheng Congyi, Wang Fen, Chen Wenqiang

Abstract excerpt

BACKGROUND: Observational studies have consistently reported positive associations between inflammatory biomarkers and the risk of developing aortic stenosis (AS). However, it is crucial to acknowledge that conventional observational studies are prone to various forms of bias, including reverse causation and residual confounding. To delve deeper into unraveling the potential causal relationship between...

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PMID: 39986193
DOI: 10.1016/j.cyto.2025.156887

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