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Article

Assessing the causal relationship between circulating immune cells and abdominal aortic aneurysm by bi-directional Mendelian randomization analysis.

Scientific reports - 14 Jun 2024

Ruan Weiqiang, Zhou Xiaoqin, Wang Ting, Liu Huizhen, Zhang Guiying, Sun Jiaoyan, Lin Ke

Abstract excerpt

Although there is an association between abdominal aortic aneurysm (AAA) and circulating immune cell phenotypes, the exact causal relationship remains unclear. This study aimed to explore the causal relationships between immune cell phenotypes and AAA risk using a bidirectional two-sample Mendelian randomization approach. Data from genome-wide association studies pertaining to 731 immune cell traits and AAA were...

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Share to Aortic Aneurysm, Abdominal
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Killer Cells, Natural

Share to Mendelian Randomization Analysis

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 38877212
DOI: 10.1038/s41598-024-64789-9
PMCID: PMC11178833

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