Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A molecular standard for circulating HBV RNA detection and quantification assays in patients with chronic hepatitis B

25 May 2024

Abstract excerpt

BackgroundCirculating HBV RNAs have been proposed as a biomarker that reflects the transcriptional activity of cccDNA and may help to evaluate HBV treatments activity. Different research assays have been proposed and, although 2 PCR-based research use only (RUO) investigational assays (IA) have been developed, the lack of standardized protocols represents an important limitation. Here we have designed and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis B Virus Studies
Share to Hepatitis C virus research
Share to RNA Interference and Gene Delivery

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39328324
DOI: 10.1016/j.jhepr.2024.101124

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A molecular standard for circulating HBV RNA detection and quantification assays in patients with chronic hepatitis BPMID 39328324Read ↗

Circulating HBV RNA: From biology to clinical applicationsSemantic proximity Read ↗

Hepatitis B virus DNA quantification with the three-in-one (3io) method allows accurate single-step differentiation of total HBV DNA and cccDNA in biopsy-size liver samples.Semantic proximity Read ↗

Functional cure of hepatitis B requires silencing covalently closed circular and integrated hepatitis B virus DNASemantic proximity Read ↗

HBV DNA replication mediated by cloned patient HBV reverse transcriptase genes from HBV genotypes A–H and its use in antiviral phenotyping assaysSemantic proximity Read ↗

Biogenesis and molecular characteristics of serum hepatitis B virus RNASemantic proximity Read ↗

A standardized assay for the quantitative detection of serum HBV RNA in chronic hepatitis B patientsSemantic proximity Read ↗

Pregenomic RNA Launch Hepatitis B Virus Replication System Facilitates the Mechanistic Study of Antiviral Agents and Drug-Resistant Variants on Covalently Closed Circular DNA SynthesisSemantic proximity Read ↗

Approaches to quantifying hepatitis B virus covalently closed circular DNASemantic proximity Read ↗

Method for Quantitative HDV RNA Detection: I, Manual Workflow (Serum and Liver Tissue) and II, Fully Automated High Throughput Workflow for Diagnostic Use.Semantic proximity Read ↗

Integrated DNA estimation in tissue biopsy and detection in liquid biopsy by HBV-targeted NGS assaySemantic proximity Read ↗

Hepatitis B virus serum RNA transcript isoform composition and proportion in chronic hepatitis B patients by nanopore long-read sequencingSemantic proximity Read ↗

High-dimensional droplet digital PCR of multiple hepatitis B splice variants in serum, liver, and tissue culture.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.