Article

Integrated DNA estimation in tissue biopsy and detection in liquid biopsy by HBV-targeted NGS assay

2024-12-05

Abstract excerpt

<h4>Background & Aims</h4> Integrated HBV DNA (iDNA) plays a critical role in HBV pathogenesis, particularly in predicting treatment response and HCC. This study aimed to use an HBV hybridization-capture next-generation sequencing (HBV-NGS) assay to detect HBV-host junction sequences (HBV-JS) in a sensitive nonbiased manner to detect and estimate the iDNA fraction in tissue biopsies and HBV genetics by liquid biop...

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Literature Corpus work: 5fa61bdf-20be-5010-9c06-179f04de4099
DOI: 10.1101/2024.12.04.24318256

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