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Method for Quantitative HDV RNA Detection: I, Manual Workflow (Serum and Liver Tissue) and II, Fully Automated High Throughput Workflow for Diagnostic Use.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2024

Pflüger Lisa Sophie, Volz Tassilo, Giersch Katja, Allweiss Lena, Dandri Maura, Lütgehetmann Marc

Abstract excerpt

The hepatitis delta virus (HDV) is a small RNA virus (1700 base pairs), which uses the surface proteins of the hepatitis B virus (HBV) as an envelope. Accurate and reliable quantitative detection of HDV RNA is central for scientific and translational clinical research or diagnostic purposes. However, HDV poses challenges for nucleic acid amplification techniques: (1) the circular genome displays high...

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PMID: 39044084
DOI: 10.1007/978-1-0716-4027-2_15

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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