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Article

Potentially functional variants of PARK7 and DDR2 in ferroptosis-related genes predict survival of non-small cell lung cancer patients.

International journal of cancer - 15 Feb 2025

Wang Huilin, Liu Hongliang, Tang Xiaozhun, Lu Guojun, Luo Sheng, Du Mulong, Christiani David C, Wei Qingyi

Abstract excerpt

Ferroptosis, a form of regulated cell death, is characterized by iron-dependent lipid peroxidation. It is recognized increasingly for its pivotal role in both cancer development and the response to cancer treatments. We assessed associations between 370,027 single-nucleotide polymorphisms (SNPs) within 467 ferroptosis-related genes and survival of non-small cell lung cancer (NSCLC) patients. Data from the...

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Source

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Identifiers

PMID: 39319523
DOI: 10.1002/ijc.35197
PMCID: PMC11661923

Genes

DDR2
PARK7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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