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Article

Genetic variants in DDO and PEX5L in peroxisome-related pathways predict non-small cell lung cancer survival.

Molecular carcinogenesis - 1 Jul 2022

Chen Allan S, Liu Hongliang, Wu Yufeng, Luo Sheng, Patz Edward F, Glass Carolyn, Su Li, Du Mulong, Christiani David C, Wei Qingyi

Abstract excerpt

Peroxisomes play a role in lipid metabolism and regulation of reactive oxygen species, but its role in development and progression of non-small cell lung cancer (NSCLC) is not well understood. Here, we investigated the associations between 9708 single-nucleotide polymorphisms (SNPs) in 113 genes in the peroxisome-related pathways and survival of NSCLC patients from the Prostate, Lung, Colorectal, and Ovarian...

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PMID: 35502931
DOI: 10.1002/mc.23400

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