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Article

Ferroptosis related CPT1A and GDF15 gene polymorphisms are risk factors for lung adenocarcinoma: A case-control study.

Gene - 15 Jan 2025

Zhang Xing, Wang Rong, Zhang Xia, Yang Yanli, Tian Ruifen

Abstract excerpt

BACKGROUND: Ferroptosis is not only a consequence of inflammation, but also a dynamic process. Recent bioinformatics analysis suggests that ferroptosis related genes might be associated with lung adenocarcinoma (LUAD). CPT1A and GDF15 are critical for the process of ferroptosis and development of inflammation; however, little study focused on the mutation level of these genes in patients with LUAD. METHODS: The...

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Identifiers

PMID: 39401734
DOI: 10.1016/j.gene.2024.149002

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