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Article

Genetic variants of genes in the Notch signaling pathway predict overall survival of non-small cell lung cancer patients in the PLCO study.

Oncotarget - 20 Sept 2016

Xu Yinghui, Wang Yanru, Liu Hongliang, Kang Xiaozheng, Li Wei, Wei Qingyi

Abstract excerpt

The Notch signaling pathway has been shown to have biological significance and therapeutic application in non-small cell lung cancer (NSCLC). We hypothesize that genetic variants of genes in the Notch signaling pathway are associated with overall survival (OS) of NSCLC patients. To test this hypothesis, we performed multivariate Cox proportional hazards regression analysis to evaluate associations of 19,571...

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Share to Carcinoma, Non-Small-Cell Lung
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27557513
DOI: 10.18632/oncotarget.11436
PMCID: PMC5308685

Genes

TLE1
ADAM12
DTX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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