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Integrative Analysis of Ferroptosis-Related Genes in Small Cell Lung Cancer for the Identification of Biomarkers and Therapeutic Targets

28 Jun 2023

Abstract excerpt

Background: Ferroptosis is an iron-dependent programmed cell death mode induced by the toxic buildup of phospholipid peroxidation. Although it is known to affect the initiation and growth of tumors, the association between ferroptosis-related genes (FRGs) and small cell lung cancer (SCLC) has yet to be established. Methods: We used the gene expression omnibus (GEO) and ferroptosis database (FerrDb) to acquire...

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PMID: 37395033
DOI: 10.31083/j.fbl2806125

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