Article
Comparative Analysis of Comprehensive Genomic Profile in Thymomas and Recurrent Thymomas Reveals Potentially Actionable Mutations for Target Therapies
2024-07-17
Abstract excerpt
CGP do not substantially differ between initial tumor vs tumor recurrence and recurrent thymomas vs non-recurrent thymomas. Cell-cycle control genes alterations are associated with an early recurrence after thymectomy. Multiple target therapies are potentially available by performing a comprehensive CGP, suggesting that a precision medicine approach on these patients could be further explored.
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Identifiers and source
- Literature Corpus work
- f9d0a421-d545-5361-bce9-3f6f1b3d8c50
- DOI
- 10.20944/preprints202407.1356.v1
