Cellular Senescence: What, Why, and How.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Cellular Senescence: What, Why, and How.

Wounds : a compendium of clinical research and practice - 1 Jun 2017

Regulski Matthew J

Abstract excerpt

Cellular senescence is a process that results from a variety of stresses and leads to a state of irreversible growth arrest. Senescent cells accumulate during aging and have been implicated in promoting a variety of age-related diseases. Cellular senescence may play an important role in tumor suppression, wound healing, and protection against tissue fibrosis; however, accumulating evidence that senescent cells...

Topics

Aging
Cell Cycle Checkpoints
Cell Transformation, Neoplastic
Cellular Senescence
Chronic Disease
DNA Damage
Humans
Phenotype
Secretory Pathway
Wnt Signaling Pathway
Wound Healing

Source

Open in PubMed

Identifiers

PMID: 28682291

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics