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Article

Cellular Senescence in Health, Disease, and Lens Aging

2025-01-14

Abstract excerpt

<h4>Background: </h4> Cellular senescence is a state of irreversible cell cycle arrest that serves as a critical regulator of tissue homeostasis, aging, and disease. While transient senes-cence contributes to development, wound healing, and tumor suppression, chronic senescence drives inflammation, tissue dysfunction, and age-related pathologies, in-cluding cataracts. Lens epithelial cells (LECs), essential for ma...

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Literature Corpus work
c25c7da2-c866-5060-a6e1-59cb3d7fa08c
DOI
10.20944/preprints202501.1109.v1
Open publication

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