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Cellular senescence in the aging retina and developments of senotherapies for age-related macular degeneration

22 Jan 2021

Abstract excerpt

Age-related macular degeneration (AMD), a degenerative disease in the central macula area of the neuroretina and the supporting retinal pigment epithelium, is the most common cause of vision loss in the elderly. Although advances have been made, treatment to prevent the progressive degeneration is lacking. Besides the association of innate immune pathway genes with AMD susceptibility, environmental stress- and...

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PMID: 33482879
DOI: 10.1186/s12974-021-02088-0

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