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Article

The impact of genetic variations in the serotonergic system on symptom severity and clinical outcome in functional neurological disorders.

Journal of psychosomatic research - 1 Nov 2024

Weber Samantha, Rey Álvarez Lucía Trinidad, Ansede-Bermejo Juan, Cruz Raquel, Del Real Álvaro, Bühler Janine, Carracedo Ángel, Aybek Selma

Abstract excerpt

OBJECTIVE: We studied gene-environment, as well as gene-gene interaction to elucidate their effects on symptom severity and predict clinical outcomes in functional neurological disorders (FND). METHODS: Eighty-five patients with mixed FND were genotyped for ten single-nucleotide polymorphisms (SNP) from seven different stress-related genes. We tested cross-sectionally the association between genotype and the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 39236646
DOI: 10.1016/j.jpsychores.2024.111909

Genes

TPH1
TPH2
BDNF
CIT
OXTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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