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Article

Effects of TPH2 gene variation and childhood trauma on the clinical and circuit-level phenotype of functional movement disorders.

Journal of neurology, neurosurgery, and psychiatry - 1 Aug 2020

Spagnolo Primavera A, Norato Gina, Maurer Carine W, Goldman David, Hodgkinson Colin, Horovitz Silvina, Hallett Mark

Abstract excerpt

BACKGROUND: Functional movement disorders (FMDs), part of the wide spectrum of functional neurological disorders (conversion disorders), are common and often associated with a poor prognosis. Nevertheless, little is known about their neurobiological underpinnings, particularly with regard to the contribution of genetic factors. Because FMD and stress-related disorders share a common core of biobehavioural...

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Identifiers

PMID: 32576619
DOI: 10.1136/jnnp-2019-322636
PMCID: PMC7402460

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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