Article
The interaction between neutrophils and atrial myocytes in the occurrence and development of atrial fibrillation.
BMC cardiovascular disorders - 27 Sept 2024
Li Tao, Wang Yan, Wan Jie, Duan Yu, Xu Yang, Yang Mao
Abstract excerpt
BACKGROUND: Atrial fibrillation (AF) is one of the most prevalent sustained cardiac arrhythmias, strongly associated with neutrophils. However, the underlying mechanism remain unclear. This study aims to explore the interaction between neutrophils and atrial myocytes in the pathogenesis of AF. METHODS: Patch-clamp was employed to record the action potential duration (APD) and ion channels in HL-1 cells. Flow...
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