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Article

Human iPSC modelling of a familial form of atrial fibrillation reveals a gain of function of If and ICaL in patient-derived cardiomyocytes

27 Aug 2019

Abstract excerpt

AIMS: Atrial fibrillation (AF) is the most common type of cardiac arrhythmias, whose incidence is likely to increase with the aging of the population. It is considered a progressive condition, frequently observed as a complication of other cardiovascular disorders. However, recent genetic studies revealed the presence of several mutations and variants linked to AF, findings that define AF as a multifactorial...

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Share to Atrial Fibrillation Management and Outcomes
Share to Cardiac Arrhythmias and Treatments
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PMID: 31504264
DOI: 10.1093/cvr/cvz217

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