Article
Correlation between T cell receptor gamma delta isotypic forms and cytotoxic activity: analysis with human T cell clones and lines.
Cellular immunology - 1 Feb 1990
Dastot H, Schmid M, Gontier C, Amiot M, Mathieu-Mahul D, Bensussan A, Boumsell L
Abstract excerpt
Three biochemically distinct isotypic forms of the human T cell receptor (TcR) gamma delta structure can be expressed at the cell membrane. This unique variation in structure of TcR, which is due to C gamma gene segments utilization, prompted us to look for isotype-association functional differences. In this regard, we have developed human T cell clones or lines from normal thymus or peripheral blood from several...
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