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Dynamic prostate cancer transcriptome analysis delineates the trajectory to disease progression

2 Dec 2021

Abstract excerpt

Comprehensive genomic studies have delineated key driver mutations linked to disease progression for most cancers. However, corresponding transcriptional changes remain largely elusive because of the bias associated with cross-study analysis. Here, we overcome these hurdles and generate a comprehensive prostate cancer transcriptome atlas that describes the roadmap to tumor progression in a qualitative and...

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PMID: 34857732
DOI: 10.1038/s41467-021-26840-5

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