Article
Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states
10 Jan 2022
Abstract excerpt
Prostate cancer is the second most common malignancy in men worldwide and consists of a mixture of tumor and non-tumor cell types. To characterize the prostate cancer tumor microenvironment, we perform single-cell RNA-sequencing on prostate biopsies, prostatectomy specimens, and patient-derived organoids from localized prostate cancer patients. We uncover heterogeneous cellular states in prostate epithelial cells...
Topics
Join the communities discussing this publication.