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Article

Gene expression-phenotype association study reveals the dual role of TNF-α/TNFR1 signaling axis in confined breast cancer cell migration.

Life sciences - 1 Oct 2024

Cruceriu Daniel, Balacescu Loredana, Baldasici Oana, Gaal Orsolya Ildiko, Balacescu Ovidiu, Russom Aman, Irimia Daniel, Tudoran Oana

Abstract excerpt

AIMS: While enhanced tumor cell migration is a key process in the tumor dissemination, mechanistic insights into causal relationships between tumor cells and mechanical confinement are still limited. Here we combine the use of microfluidic platforms to characterize confined cell migration with genomic tools to systematically unravel the global signaling landscape associated with the migratory phenotype of breast...

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Share to Breast Neoplasms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Neoplastic

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Share to Receptors, Tumor Necrosis Factor, Type I

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Share to Tumor Necrosis Factor-alpha

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Identifiers

PMID: 39151886
DOI: 10.1016/j.lfs.2024.122982

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