Article
Pro-adhesive phenotype of normal endothelial cells responding to metastatic breast cancer cell conditioned medium is linked to NFκB-mediated transcriptomic regulation.
International journal of oncology - 1 Nov 2016
Mejía-Rangel Janini, Córdova Emilio, Orozco Lorena, Ventura-Gallegos José Luis, Mitre-Aguilar Irma, Escalona-Guzmán Alma, Vadillo Felipe, Vázquez-Prado José, Gariglio Patricio, Zentella-Dehesa Alejandro
Abstract excerpt
Tumor microenvironment is an important promoter of tumorigenesis in all forms of breast cancer and has been associated with the risk of metastasis in the different breast cancer subtypes including the more frequent luminal subtypes that encompass 60% of cancer patients. Adhesive properties of endothelial cells (ECs) are strikingly affected during cancer cell dissemination and are related to functional changes of...
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