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Article

A versatile residue numbering scheme for Nav and Cav channels.

Cell chemical biology - 15 Aug 2024

Jin Xueqin, Huang Jian, Wang Huan, Wang Kan, Yan Nieng

Abstract excerpt

Voltage-gated sodium (Nav) and calcium (Cav) channels are responsible for the initiation of electrical signals. They have long been targeted for the treatment of various diseases. The mounting number of cryoelectron microscopy (cryo-EM) structures for diverse subtypes of Nav and Cav channels from multiple organisms necessitates a generic residue numbering system to establish the structure-function relationship...

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Identifiers

PMID: 39151406
DOI: 10.1016/j.chembiol.2024.07.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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