Article
[Clonal hematopoiesis: causes and clinical implications].
Zeitschrift fur Gerontologie und Geriatrie - 1 Feb 2023
Burchert Andreas
Abstract excerpt
Clonal hematopoiesis of indeterminate potential (CHIP) refers to hematopoiesis from stem cells with mutations in leukemia-associated driver genes. These confer increased stress tolerance and expansive potential to stem cell clones. Patients with CHIP are hematologically healthy. The main risk factor for the development of CHIP is age or chronic inflammatory processes associated with aging, so-called...
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